2007

Key: Faculty · Undergraduate Students · Graduate Students


Papers

  • Kasi, G. K; Dollahon, N. R.; Ahmadi, T. S. Fabrication and characterization of solid PbI2 nanocrystals, J. Phys.D: Appl. Phys., 2007, 40, 1778, 2007.
  • Brown, D. G.; Horchler, C. L.; Bare, T. M.; et al. Pryridazinoquinolinetriones as NMDA Glycine-Site Antagonists with Oral Antinociceptive Activity in a Model of Neuropathic Pain, J. Med. Chem., 2007, 50, 3113-3131.
  • Weinstein, R. D.; Richards, J.; Thai, S. D.; Omiatek, D. M.; Bessel, C. A.; Faulkner, C. J.; Othman, S.; Jennings, G. K. Characterization of Self-Assembled Monolayers from Lithium Dialkyldithiocarbamate Salts, Langmuir, 2007, 23(5), 2887-2891.
  • Mascelli, M.A.; Zhou, H.; Sweet, R.; Getsy, J.; Davis, H.M.; Graham, J. and Abernethy, D. Molecular, Biologic and Pharmacokinetic Properties of Monoclonal Antibodies: Impact of These Parameters on Early Clinical Development, J Clin Pharm, 45(5), 553-565, 2007.
  • Zhou, H.; Jang, H.; Bouman-Thio, E.; Xu, Z.; Marini, J.; Pendley, C.; Jiao, Q.; Shankar, G.; Marciniak, S.; Fleischmann, R.M.; Cohen, S.B.; Rahman, M.U.; Baker, D.; Mascelli, M.A.; Everitt, D.E.; Davis, H.M. Pharmacokinetics and Safety of Golimumab, a Fully Human Anti-TNFa  Monoclonal Antibody, in Subjects with Rheumatoid Arthritis, J Clin Pharm., 47, 383-396, 2007.
  • Mullamitha, S.; Ton, C.; Parker, G.J.M.; Davis, H.M., and Jayson, G.C. Phase I Evaluation of a Fully Human Anti-av Integrin Monoclonal Antibody (CNTO 95) in Patients with Advanced Solid Tumors, Clinical Cancer Research, 13 (7), 2128-2135, 2007.
  • Beckman, R.; Weiner, L.M., and Davis, H.M. Antibody Constructs in Cancer Therapy: Protein Engineering Strategies to Improve Exposure in Solid Tumors, Target Journal: Cancer, 109 (2), 170-179, 2007.
  • Nemeth, J.A.; Nakada, M.T.; Trikha, M.; Lang, Z.; Gordon, M.S.; Jayson, G.C.; Corringham, R.; Davis, H.M., and Beckman, R.A., av -Integrins as Therapeutic Targets in Oncology, Cancer Investigation, 25 (7), 632-646, 2007.
  • Schubert, J. W.; Dudley, T. J.; Ohta, B. K. Theoretical investigation of Lone Pair Inversions, Ring Openings, and Hydride Shifts in O-Methylated Epoxides, J. Org. Chem., 2007, 72, 2452-2459.
  • Bare, T.M.; Brown, D.G.; Horchler, C.L.; Murphy, M.; Urbanek, R.A.; Alford, V.; Barlaam, C.; Dyroff, M. C.; Empfield, J.B.; Forst, J.M.; Herzog, K.A.; Keith, R.A.; Kirschner, A.S.; Lee, C-M. C.; Lewis, J.; McLaren, F.M.; Neilson, K.L.; Steelman, G.B.; Trivedi, S.; Vacek, E.P.; Xiao, W. Pyridazinoquinolinetriones as NMDA Glycine-Site Antagonists with Oral Antinociceptive Activity in a Model of Neuropathic Pain, J. Med. Chem., 2007, 50 (13), 3113-3131.
  • Grannas, A. M.; Jones, A. E.; Dibb, J.; Ammann, M.; Anastasio, C.; Beine, H.; Bergin, M.; Bottenheim, J.; Boxe, C. S.; Carver, G.; Crawford, J. H.; Domine, F.; Frey, M. M.; Guzman, M. I.; Heard, D.; Helmig, D.; Hoffmann, M. R.; Honrath, R. E.; Huey, L. G.; Jacobi, H.-W.; Klan, P.; McConnell, J.; Sander, R.; Savarino, J.; Shepson, P. B.; Simpson, W. R.; Sodeau, J.; von Glasgow, R.; Weller, R.; Wolff, E.; Zhu, T.  An overview of snow photochemistry: evidence mechanisms and impacts, Atmos. Chem. Phys., 2007, 7, 4329-4373.
  • Hockaday, W. C.; Grannas, A. M.; Kim, S.; Hatcher, P. G. The transformation and mobility of charcoal black carbon in a fire-impacted watershed, Geochimica et Cosmochimica Acta, 2007, 71(14), 3432-3445.
  • Grannas, A. M.; Bausch, A. R.; Mahanna, K. M.  Enhanced aqueous photochemical reaction rates after freezing, J. Phys. Chem. A, 2007, 111, 11043-11049.
  • Baxter, E.W, Conway, K.A, Kennis, L., Bischoff, F., Mercken, M.H., De Winter, H.L., Reynolds, C.H., Tounge, B.A., Luo, C., Scott, M.K., Huang, Y, Bracken, M, Pieters, S.M.A., Berthelot, D.J.C., Masure, S, Bruinzeel, W.D.,  Jordan, A.D., Parker, M.H., Boyd, R.E., Qu, J., Alexander, R.S., Brenneman, D.E., Reitz, A.B., 2-Amino-3,4-dihydroquinazolines as Inhibitors of BACE-1 (ß- Site APP Cleaving Enzyme):  Use of Structure Based Design to a Micromolar Hit into a Nanomolar Lead. J. Med. Chem., 2007, 50,  4261-4264.
  • Gibson, H. W.; Wang, H.; Slebodnick, C.; Merola, J.; Kassel, W. S.; Rheingold, A. L. Isomeric 2,6-pyridino-cryptands based on dibenzo-24-crown-8, J. Org. Chem., 2007, 72, 3381-3393.
  • Rowhani, T.; Lagalante, A. F. A Colorimetric Assay for the Determination of Polyhexamethylene Biguanide in Pool and Spa Water using Nickel-Nioxime, Talanta, 2007, 71(2), 964-970.
  • Lagalante, A. F.; Greenbacker, P. W. Flow injection analysis of imidacloprid in natural waters and agricultural matrixes by photochemical dissociation, chemical reduction, and nitric oxide chemiluminescence detection, Anal. Chim. Acta, 2007, 590, 151-158.
  • Lagalante, A. F.; Montgomery, M. E.; Calvosa, F. C.; Mirzabeigi, M. N. Characterization of Terpenoid Volatiles from Cultivars of Eastern Hemlock (Tsuga canadensis), J. Agric. Food Chem., 2007, 55(26), 10850-10856.
  •  Tierney, J.; Colasante, N.; Eagles, J.; Kelly, S.; Lehmike, G.; Lucas, O.; Mannikarottu, C.; Mehmood, O.; Nguyen, M. D.; Raj, V.; Tsai, J.; Koyfman, V.; Mascavage, L. M. and Lagalante, A. F. A Comparison of Substituent Effects Using 13C Chemical Shifts for a Series of Substituted 2-Phenyl-3-pyridyl-1,3-thiazolidin-4-ones Compared to Similarly Substituted 1,3-thiazolidin-4-ones Heterocyclic Communications, 2007, 13, 335.
  • Ohta, B. K.; Hough, R. E.; Schubert, J. W. Evidence for b-Chlorocarbenium and b-Bromocarbenium Ions, Org. Lett., 2007, 9, 2317-2320.
  • Ullrich, John W.; Mewshaw, R., March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure. Sixth Edition, by Michael B. Smith and Jerry March, Journal of Medicinal Chemistry, 2007, 50 (9), 2279-2280.
  • Ullrich, John W.; Singhaus, R.; Unwalla, R.; Harris, H.; Mewshaw, R., Estrogen receptor b ligands: Design and synthesis of new 2-phenyl-isoindole-1,3-diones, Bioorganic & Medicinal Chemistry Letters, 2007, 118-122.

Presentations

  • Pharmacokinetics and Exposure-Response Relationship of Ustekinumab, a Human Mononclonal Antibody to Interleukin-12/23 in Patients with Moderate to Severe Crohn’s Disease, Fasanmade, A.; Adedokun, O.; Johanns, J.; Zhou, H.; Davis, H.M. and Blank, M. Blank, DDW, 2008.
  • Population-based Assessment of Concomitant Methotrexate on Infliximab Pharmacokinetics in Patients with Psoriatic Arthritis, Zhang, S.; Seitz, K.; Fasanmade, A.; Xu, Z.; Pendley, C.; Beutler, A., Davis, H.M., and H. Zhou, ASCPT, 2007.
  • Use of Phage Display and Selection Criteria to Design Human Anti-Idiotypic Antibodies that Mimic a Polyclonal Primate Immune Response, Schantz, A.; Tornetta, M.; Fisher, D.; O’Neil, K.; Knight, D.; Davis, H.; Sweet, R. and Tsui P.  AAPS Biotechnology National Conference, 2007.
  • Exposure-Efficiency Assessment of Golimumab in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy: Application of Population Pharmacokinetic/Pharmacodynamic Modeling, Zhou, H.; Rahman, M.U.; Wagner, C.; Han, J.; Baker, D.; Jang, H. and Davis H.M., ACR, 2007.
  • A Phase I, Single Ascending Dose Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of Subcutaneous Administration of an Erythropoeitic Mimetic Antibody Fusion Protein (CNTO 528) in Healthy Male Subjects, Bouman-Thio, E.; Franson, K.; Burggraaf J. and Davis H.M., ASCPT, March 2007.
  • Dudley, T. J.; Gordon, M. S., "Theoretical investigation of the excited state proton transfer in the 7-azaindole dimer," Middle Atlantic Regional Meeting of the American Chemical Society, Ursinus College, May 16-18, 2007.
  • Dudley, T. J., "Using Computational Chemistry to Understand Ions," Invited Presentation, Long Island University, Brooklyn, NY, April 24, 2007.
  • Licisyn, T. A.; Giuliano, R. M.; Boyko, W. J., "Cyclopropyl glycoside derivatives and their use in glycopeptides synthesis," Middle Atlantic Regional Meeting of the American Chemical Society, Ursinus College, May 16-18, 2007.
  • Flores, B. A.; Giuliano, R. M., "Addition of benzenesulfinic acid to glycals: Synthesis of C-Glycoside precursors," Philadelphia Organic Chemist’s Club Poster Session, April 19, 2007.
  • Rowland, G.; Grannas, A. M., "A solid-phase chemical actinometer for snowpack solar irradiation measurements," National Meeting of the American Geophysical Union, San Francisco, CA, December, 2007.
  • Smith, W.; Grannas, A. M., "High school students as science researchers: Opportunities and challenges,” National Meeting of the American Geophysical Union, San Francisco, CA, December 2007.
  • Grannas, A. M.; Rowland, G.; Sprenkle, A.; Bausch, A., “Photochemical transformations of trace persistent organic pollutants in snow and ice,” National Meeting of the American Geophysical Union, San Francisco, CA, December, 2007.
  • Paul, J.; Grannas, A. M., "Behavior of Pollutants in Arctic Sediments," National Meeting of the American Chemical Society, Boston, MA, August 2007.
  • Calvosa, F. C.; Lagalante, A.F., “Determination of polybrominated diphenyl ethers (PBDEs) in dust by SFE-GC-EI/MS/MS and GC-NCI/MS” 28th Annual Meeting of SETAC North America, Milwaukee, WI, November 11-14, 2007.
  • Tierney, J.; Lagalante, A. F., "The mass spectra and fragmentation patterns for two series of 1,3-thiazolidin-4-ones," Middle Atlantic Regional Meeting of the American Chemical Society, Ursinus College, May 16-18, 2007.
  • Hess, K. L.; Papalaskari, M.; Weinstein, R.; Styer, R.; Way, T.; Lagalante, A. F., "Creation of the Milwaukee School of Magic," Frontiers in Education Conference, Milwaukee, WI, October 10-13, 2007.
  • Papalaskari, M.; Hess, K. L.; Lagalante, A. F.; Nadi, N.; Styer, R.; Way, T.; Weinstein, R., "Work in Progress - Engineering the Magic School Creativity and Innovation in Context," Frontiers in Education Conference, Milwaukee, WI, October 10-13, 2007.
  • Lagalante, A. F., “Cross-Curriculum implementation of art in chemistry at Villanova University,” Invited Talk, 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007.
  • Oswald, T.; Lagalante, A. F., “Novel approaches to sampling and detection of PBDEs in dust using SPME and APPI-LC-MS-MS,” 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007.
  • Norbutus, A.; Lagalante, A. F., “Spectroscopic examination of a Dutch genre oil painting,” 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007.
  • Cook, F.; Lagalante, A. F., “LC-MS-MS analysis of imidacloprid and metabolites in hemlock trees,” 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007.
  • Calvosa, F.; Lagalante, A. F., “Determination of polybrominated diphenyl ethers (PBDEs) in dust by SFE-GC-MS-MS,” 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007.
  • Conway, A. E.; Martey-Ochola, C. A., "Cigarette smoke effects on the AKT pathway in normal human lung fibroblasts," 233rd ACS National Meeting, Chicago, IL, March 25-29, 2007.
  • Morton, L. A., Zubris, D. L., "Synthesis and characterization of PhP(η5-t-BuCp)2ZrCl2: A novel ansa-zirconocene with a phosphine linker," 233rd ACS National Meeting, Chicago, IL, March 25-29, 2007.
  • Scupp, T. M.; Dudley, T. J.; Ohta, B. K.  "Activation of Weakly Nucleophilic Solvents by Halonium Ions,” Villanova Undergraduate Summer Research Poster Session, Villanova, PA, Fall 2007.
  • Aran-Terol, P.; Ohta, B. K. "The Structure of Tetramethylethylene Iodonium Ion," Villanova Undergraduate Summer Research Poster Session, Villanova, PA, Fall 2007.
  • Ohta, B. K. "Structural Implications of the Absence of Equilibrium Isotope Shifts in Aziridinium Imide,” ACS National Meeting, Chicago, IL, March 25-29, 2007.
  • Schubert, J. W.; Ohta, B. K. "Experimental and Theoretical Investigations of Chloronium Ions,” ACS National Meeting, Chicago, IL, March 25-29, 2007.
  • Johns, G. G.; Conway, A. E.; Selinsky, B. S., "Structural requirements for time-dependent and time-independent inhibition of prostaglandin synthase I," Middle Atlantic Regional Meeting of the American Chemical Society, Ursinus College, May 16-18, 2007.
  • Zubris, D. L.; Morton, L. A.; Thai, S. D., "Synthesis and characterization of novel ansa-zirconocenes with a phosphine linker," Middle Atlantic Regional Meeting of the American Chemical Society, Ursinus College, May 16-18, 2007.
  • Thai, S. D.; Daundikhed, N. S.; Zubris, D. L., "Progress toward the synthesis of [(Me2Si)(PhC=CPh){η5-C5H2-4-t-Bu}2]ZrCl2," 233rd ACS National Meeting, Chicago, IL, March 25-29, 2007.
  • Ullrich, John W.; Morris, R.; Bernotas, R.; Kaufman, D.; Nambi, P.; Quinet, E.; Chen, L.; Halpern, A.; Liu, Q.; Savio, D.; Basso, M.; Unwalla, R.; Wilhelmsson, A.; Goos Nilsson, A.; Ursu, C.; Arnelof, E.; Sandberg, J.; Enroth, C.; Wrobel, J., “Synthesis and LXR activity of 4-(3-(phenylethynl)pheny) quinolines” 233rd ACS National Meeting, Chicago, Il, United States, Mar. 25-14, 2007   
  • Zubris, D. L.; Morton, L. A.; Thai, S. D., "Synthesis and characterization of novel ansa-zirconocenes with a phosphine linker," Middle Atlantic Regional Meeting of the American Chemical Society, Ursinus College, May 16-18, 2007.
  • Morton, L. A.; Zubris, D. L., "Synthesis and characterization of PhP(h-5-t-BuCp)2ZrCl2: A novel ansa-zirconocene with a phosphine linker," National Meeting of the American Chemical Society, Chicago, IL, March 25-29, 2007.
  • Thai, S. D.; Daundikhed, N. S.; Zubris, D. L., "Progress towards the synthesis of [(Me2Si)(PhC=CPh){h-5-C5H2-4-t-Bu}2ZrCl2," National Meeting of the American Chemical Society, Chicago, IL, March 25-29, 2007.
  • Thai, S. D.; Daundikhed, N. S.; Zubris, D. L., "Progress towards the synthesis of [(Me2Si)(PhC=CPh){h-5-C5H2-4-t-Bu}2ZrCl2," Sigma Xi Research Day, Villanova University, April 27, 2007.