2008

Key: Faculty · Undergraduate Students · Graduate Students


Papers

  • Becker, I.  Preparation of Derivatives of 1-(2-Pyrimidinyl) piperazine as Potentiall Antianxiety, Antidepressant, and Antipsychotic Agents, J. Heterocyclic Chem. 2008, 45,1005.
  • Bouman-Thio, E.; Franson, K.; Miller, B.; Getsy, J.; Cohen, A.; Bai, S.; Yohrling, J.; Frederick, B.; Marciniak, S.; Jiao, Q.; ang, H.; Davis, H. M.; Burggraaf, J. A Phase I, Single and Fractionated, Ascending-Dose Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of an Erythropoietin Mimetic Antibody Fusion Protein (CNTO 528) in Healthy Male Subjects, J. Clin. Pharmacol, 2008, 48, 1197-1207.
  • Xu, Z.; Seitz, K.; Fasanmade, A.; Ford, J.; Williamson, P.; Xu, W.; Davis, H.M.; Zhou, H. Population Pharmacokinetics of Infliximab in Patients with Ankylosing Spondylitis, J. Clin. Pharmacol, 2008, 48, 681-695.
  • Sears, K. C.; Ferguson, J. W.; Dudley, T. J.; Houk, R. S.; Gordon, M. S. Theoretical Investigation of Small Polyatomic Ions Observed in Inductively Coupled Plasma – Mass Spectrometry:  HxCO+ and HxN2+ (x=1,2,3), J. Phys. Chem. A, 2008, 112, 2610-2617.
  • Basava, V.; Flores, B.; Giovine, M.; Licisyn, T.; Walck, K.; Boyko, W.; Giuliano, R. M. Addition Reactions of Benzenesulfinic Acid with Glycals and 1,2-Dibromosugars, Journal of Carbohydrate Chemistry, 2008, 27, 389-400.
  • Giuliano, R. M., Editor., “New Directions in the Chemistry and Biology of Carbohydrates,” Current Topics in Medicinal Chemistry, 2008, 8 63-170.
  • Breen, M. E.; Tameze, S. L.; Dougherty, W. G.; Kassel, W. S.; Wheeler, K. A. Structural Studies of Enantiomers, Racemates, and Quasiracemates. 2-(3-Bromophenoxy)propionic Acid and 2-(3-Methoxyphenoxy)propionic Acid, Crystal Growth & Design, 2008, 8, 3863-3870.
  • Grotjahn, D. B.; Zeng, X.; Cooksy, A. L.; Kassel, W. S.; DiPasquale, A. G.; Zakharov, L. N.; Rheingold, A. L. Experimental and Computational Study of the Transformation of Terminal Alkynes to Vinylidene Ligands on trans-(Chloro)bis(phosphine)Rh Fragments and Effects of Phosphine Substituents, Organometallics, 2008, 27, 3626-3626.
  • Lineberry, A. M.; Benjamin, E. T.; Davis, R. E.; Kassel, W. S.; Wheeler, K. A. Structural Studies of Racemates and Quasiracemates: Chloro, Bromo, and Methyl Adducts of 2-Phenoxypropionic Acid, Crystal Growth & Design, 2008, 8, 612-619.
  • Maddox, A. F.; Rheingold, A. L.; Golen, J. A.; Kassel, W. S.; Nataro, C. Taniaphos and Walphos ligands: Oxidative electrochemistry and complexation. Synthesis, characterization, oxidative electrochemistry and X-ray structures of ((Taniaphos/Walphos)MCl2 (M=Pd or Pt), Inorganica chimica acta, 2008, 361, 3283-3293.
  • Pakkirisamy, T.; Venkatasubbaiah, K.; Kassel, W. S.; Rheingold, A. L.; Jäkle, F. Examination of the Pyridine Binding to the Bifunctional Lewis Acid B,B′-Diphenyldiboradiferrocene, Organometallics 2008, 27, 3056-3064.
  • Lagalante, A. F.; Oswald, T. D. Analysis of Polybrominated Diphenyl Ethers (PBDEs) by Liquid Chromatography with Negative-Ion Atmospheric Pressure Photoionization Tandem Mass Spectrometry (LC/NI-APPI/MS/MS): Application to House Dust Anal. Bioanal. Chem. 2008, 391(6), 2249-2256.
  • Ohta, B. K.; Scupp, T. M.; Dudley, T. J. Theoretical Evidence for the Nucleophilic Addition of Sulfur Dioxide to 1,2-Bridged Chloronium and Bromonium Ions, J. Org. Chem., 2008, 73, 7052-7059.
  • Bellofatto, V.; Palenchar, J.B. RNA interference as a genetic tool in trypanosomes, Methods Mol. Biol., 2008, 442, 83-94.
  • Zubris, D. L. Doubly Bridged Metallocenes for Stereoselective Propylene Polymerization, In Stereoselective Polymerization with Single-Site Catalysts, Baugh, L. S.; Canich, J. M. Eds.; Taylor and Francis:  Boca Raton, FL, 2008, pp. 101-134.
  • Axtell, J. C.; Thai, S. D.; Morton, L. A.; Kassel, W. S.; Dougherty, W. G.; Zubris, D. L. Synthesis of rac/meso-{PhP(3-t-Bu-C5H3)2}Zr{RN(CH2)3NR}, structural analysis of rac-{PhP(3-t-Bu-C5H3)2}Zr{RN(CH2)3NR} (where R is SiMe3 or Ph), and meso to rac isomerization, J. Organomet. Chem., 2008, 693, 3741-3750.
  • Steves, J. E.; Kennedy, M. D.; Chiang, K. P.; Kassel, W. S.; Dougherty, W. G.; Dudley, T. J.; Zubris, D. L. Synthesis of a bulky bis(imino)pyridine compound: a methodology for systematic variation of steric bulk and energetic implications for metalation, Dalton Trans., 2009, DOI: 10.1039/b815987d.

Patents

  • Hoffmann, M. J.; Demaio, W.; Wang, J.; Ullrich, J. W.  Isolated hydroxy and n-oxide metabolites and derivatives of O-desmethyl-venlafaxine and methods of treatment.  PCT Int. Appl., (2008), 103pp.
  • Bernotas, R. C.; Singhaus, R. R., Jr.; Ullrich, J. W.; Kaufman, D. H.; Morris, R. L.; Wrobel, J. E.; Hu, B.; Jetter, J. W.; Collini, M. D.; Travins, J. M.; Magolda, R. L.  Quinoline compounds as liver X receptor modulators and their preparation, pharmaceutical compositions and use in the treatment of LXR-mediated diseases.

Presentations

  • Sowers, R., Reif, A., Casillas, E. " Biomimetic Approach to the Synthesis of the Tricyclic Diterpene Sarcoglane,"
  • Gulacsy, C.,  Quigley, M., Sladicka, T., Cooper, W. A., Safi, L., Harmonay, L. Shneider, S., Casillas, E. “Divinylcyclopropane Rearrangement Approach to Minimized Analogs of the Helminthosporols,” 235th National Meeting of the American Chemical Society, New Orleans, LA, April 2008.
  • Zhou, H.; Zhu, Y.; Lu, M.; Hu, C.; Liao, S.; Yeilding, N.; HM Davis, H. M., "Population-Based Exposure-Efficacy Modeling of Ustekinumab in Patients with Moderate to Severe Plaque Psoriasis,'' ACCP 37th Annual Meeting, Philadelphia, PA, 2008.
  • Xu, Z.; Lee, H.; Vu, T.; Hu, C.; Ling, J.; Baker, D.; Rahman, M. U.; Pendley, C.; Wagner, C. L. ; Davis, H. M.; Zhou, H., "Population Pharmacokinetics of Golimumab, a Human Anti-Tumor Necrosis Factor-a Monoclonal Antibody, in Patients with Rheumatoid Arthritis," ACCP 37th Annual Meeting, Philadelphia, PA, 2008.
  • Xu, Z.; Vu, T.; Lee, H.; Ling, J.; Hu, C.; Baker, D.; Beutler, A.; Pendley, C.; Wagner, C. L.; Davis, H. M.; Zhou, H., "Population Pharmacokinetics of Golimumab, a Human Anti-Tumor Necrosis Factor-a Monoclonal Antibody, in Patients with Psoriatic Arthritis," ACCP 37th Annual Meeting, Philadelphia, PA, 2008.
  • Xu, Z.; Vu, T.; Lee, H.; Hu, C.; Beutler, A.; Pendley, C.; Wagner, C. L.; Davis, H. M. ; Zhou, H., "Population Pharmacokinetics of Golimumab, a Human Anti-Tumor Necrosis Factor-a Monoclonal Antibody, in Patients with Ankylosing Spondylitis," ACCP 37th Annual Meeting, Philadelphia, PA, 2008.
  • Zhu, Y. W.; Zhou, H.; S. Liao, S.; Hu, C.;. Lu, M.; Wang, L.; Yohrling, J.; Marini, J. C.; Yeilding, N.; Davis, H. M., "Population Pharmacokinetic Modeling of Ustekinumab, a Human Anti-IL-12/23p40 Monoclonal Antibody (mAb), in Two Phase 3 Studies in Patients with Moderate to Severe Plaque Psoriasis," IXth World Congress of Clinical Pharmacology and Therapeutics, Quebec, 2008.
  • Fasanmade, A.;. Adedokun, O.; Johanns, J.; Zhou, H.; Davis, H. M.; Blank, M., "Pharmacokinetics and Exposure-Response Relationship of Ustekinumab, a Human Mononclonal Antibody to Interleukin-12/23 in Patients with Moderate to Severe Crohn’s Disease," DDW, 2008.
  • Xu, Z.; Lee, H.; Vu, T.; Hu, C.; Ling, J.; Baker, D.; Rahman, M. U.; Pendley, C.; Wagner, C. L.; Davis, H. M.; Zhou, H.,"Population Pharmacokinetics of Golimumab, a Human Anti-Tumor Necrosis Factor-a Monoclonal Antibody, in Patients with Rheumatoid Arthritis," EULAR, Paris, France, June 2008.
  • Xu, Z.; Vu, T.; Lee, H.; Ling, J.; Hu, C.; Baker, D.; Beutler, A.; Pendley, C.; Wagner, C. L.; Davis, H. M.; Zhou, H., "Population Pharmacokinetics of Golimumab, a Human Anti-Tumor Necrosis Factor-a Monoclonal Antibody, in Patients with Psoriatic Arthritis," EULAR, Paris, France, June 2008.
  • Grannas, A. M., "Photochemistry in snow and ice: Assessing the fate of organic pollutants in the Arctic," Invited Presentation, University of Maryland, College Park, MD, November 14, 2008.
  • Eisele, I. C.; Grannas, A. M., "The Distribution, Transport and Fate of Organochlorine Pollutants in the Arctic," American Geophysical Union National Meeting, San Francisco, CA, December 14-19, 2008.
  • Bausch, A. R.; Rowland, G.A.; Grannas, A. M., "Photochemical Activity of Aldrin and Dieldrin in Liquid and Frozen Aqueous Systems: Field and Laboratory Studies," American Geophysical Union National Meeting, San Francisco, CA, December 14-19, 2008.
  • Rowland, G.A.; Bausch, A. R.; Grannas, A. M., "Photochemical Transformation of Organochlorine POPs in Frozen Aqueous Systems: Field Studies at Barrow, Alaska," American Geophysical Union National Meeting, San Francisco, CA, December 14-19, 2008. 
  • Lagalante, A. F.; Oswald, T. D.; Calvosa, F. C.  “Analysis of Polybrominated Diphenyl Ethers (PBDEs) by Liquid Chromatography with Negative-Ion Atmospheric Pressure Photoionization Tandem Mass Spectrometry (LC/NI-APPI/MS/MS).  Method Validation and Application to Automobile Dust”, SETAC North America 29th Annual Meeting, Tampa, FL,  November 16-20, 2008.
  • Lagalante, A. F. “New Techniques to Evaluate Imidacloprid Metabolites” The 4th Hemlock Woolly Adelgid Symposium, Hartford, CT, February 12-14, 2008.
  • Lagalante, A. F. “Evaluating Hemlock Terpenoids” The 4th Hemlock Woolly Adelgid Symposium, Hartford, CT, February 12-14, 2008.
  • Zubris, D. L., "Synthesis of sterically hindered bis(imino)pyridine ligands," Invited Presentation, State University of New Jersey, Rutgers-Camden, Camden, NJ, March 3, 2008.