2009

Key: Faculty · Undergraduate Students · Graduate Students

Papers

  • Frahani, M.; Ahmadi, T. S.; Seif, A. A DFT study of the nuclear magnetic response of the zigzig AlN-BN and BN-AlN nanotube junctions, J. Molec. Struct.: Theochem, 2009, 913, 126-130.
  • Seif, A.; Ahmadi, T. S.; Bodaghi, A.; Hosseini, J. Influence of Mn-doping on the chemical shielding tensors of 71Ga and 15N in the armchair GaN nanotubes:  A DFT study, J. Molec. Struct.:  Theochem, 2009, 911, 19-23.
  • Zhou, H.; Zhu, Y.; Lu, M.; Hu, C.; Liao, S.; Yielding, N.; Davis, H. M.; Population-Based Exposure-Efficacy Modeling of Ustekinumab in Patients with Moderate to Severe Plaque Psoriasis, J Clin Pharmacol, published online doi:10.1177/0009343695, Nov. 2009.
  • Lu, Q.; Zheng, X.; McIntosh, T.; Davis, H. M.; Nemeth, J. F.; Pendley, C.; Wu, S-Ll; Hancock, W. S. The Development of Different Analysis Platforms with LC-MS for Pharmacokinetic Studies of Protein Drugs, Analytical Chem, 81, 8715-8723, 2009.
  • Xu, Z.; Vu, T.; Lee, H.; Hu, C.; Ling, J.;Yan, H.; Baker, D.; Beutler, A.; Pendley, C.; Wagner, C.; Davis, H. M.; Zhou, H. Population Pharmacokinetics of Golimumab, an Anti-Tumor Necrosis Factor Human Monoclonal Antibody, in Patients with Psoriatic Arthritis, J Clin Pharmacol, 49, 1056-1070, 2009.
  • Zhou, H.; Davis, H. M.; Risk-Based Clinical Pharmacology Strategy for the Assessment of Drug-Drug Interactions for Therapeutic Biologics, Drug Discovery Today, 14 (17/18, Sept), 891-898, 2009.
  • Ling,J.; Zhou, H.; Jiao, T.; Davis, H. M.; Interspecies Scaling of Therapeutic Monoclonal Antibodies: Initial Look, J Clin Pharmacol, published online doi:10.1177/0091270009337134, Oct, 2009.
  • Perez-Ruixo, J.J.; Krzyzanski, W.; Bouman-Thio, E.; Miller, B.; Bai, S.A.; Zhou, H.; Yohrling, J.; Cohen, A.; Burggraaf,K.; Franson, K.; Davis, H. M.; Pharmacokinetics and Pharmacodynamics of Erythropoietic Mimetic Antibody Fusion Protein CNTO 528 in Healthy Subjects, J Clin Pharmacokinetics, 48 (9), 601-613, 2009.
  • Zhu, Y.; Hu, C.; Lu, M.; Liao, S.; Marini, J.; Yohrling, J.; Yeilding, N.; Davis, H. M.; Zhou, H. Population Pharmacokinetic Modeling of Ustekinumab, a Human Monoclonal Antibody Targeting IL-12/23p40, in Patients with Moderate-to-Severe Plaque Psoriasis, J Clin Pharmacol, 49, 162-175, 2009
  • Ferguson, J. W.; Dudley, T. J.; Sears, K. C.; McIntyre, S. M.; Gordon, M. S.; Houk, R. S. Polyatomic ions in inductively coupled plasma – mass spectrometry.  Part II:  Origins of N2H+ and HxCO+ ions using experimental measurements combined with calculated energies and structures, Spectrochim. Acta B, 2009, 64, 690-696.
  • Steves, J. E.; Kennedy, M. D.; Chiang, K. P.; Kassel, W. S.; Dougherty, W. G.; Dudley, T. J.; Zubris, D. L. Synthesis of a bulky bis(imino)pyridine ligand:  A methodology for systematic variation of steric bulk and energetic implications for metallation, Dalton Trans., 2009, 1214-1222.
  • Burke, L. A.; Fazen, P. J. Cascading 1,3-Dipolar Cycloadditions:  Combined and Consecutive Mechanisms to Azirines up to Pentazenes and Pentazoles, Int J Quantum Chem., 2009, 109, 3613–3618.
  • Mock, M. T.; Potter, R. G.; Camaioni, D. M.; Li, J.; Dougherty, W. G.; Kassel, W. S.; Twamley, B.; DuBois, D. L. Thermodynamic Studies and Hydride Transfer Reactions from a Rhodium Complex to BX3 Compounds, J. Am. Chem. Soc., 2009, 131, 14454.
  • Beckmann, P. A.; Dougherty Jr., W. G.; Kassel, W. S. Methyl and t-butyl reorientation in an organic molecular solid. Solid State Nucl. Magn. Reson., 2009, 36, 86.
  • Kahn, S. L.; Breheney, M. K.; Martinak, S. L.; Fosbenner, S. M.; Siebert, A. R.; Kassel, W. S.; Dougherty, W. G.; Nataro, C. Synthesis, Characterization, and Electrochemistry of Compounds Containing 1-Diphenylphosphino-1’-(di-tert-butylphosphino)ferrocene (dppdtbpf), Organometallics  2009, 28, 2119.
  • Lagalante, A. F.; Oswald, T. D.; Calvosa, F. C. Polybrominated Diphenyl Ether (PBDE) Levels in Dust from Previously Owned Automobiles at United States Dealerships, Environment International, 2009, 35, 539-544.
  • Ibrahim, B. S.; Kanneganti, N.; Rieckhof, G. E.; Das, A.; Laurents, D. V.; Palenchar, J. B.; Bellofatto, V.; Wah, D. A. Structure of the C-terminal domain of transcription factor IIB from Trypanosoma brucei, Proc. Natl. Acad. Sci. U S A, 2009, 106(32), 13242-13247.
  • Banerjee, H.; Palenchar, J. B.; Lukaszewicz, M.; Bojarska, E.; Stepinski, J.; Jemielity, J.; Guranowski, A.; Ng, S.; Wah, D. A.; Darzynkiewicz, E.; Bellofatto, V. Identification of the HIT-45 protein from Trypanosoma brucei as an FHIT protein/dinucleoside triphosphatase: substrate specificity studies on the recombinant and endogenous proteins, RNA, 2009, 15(8), 1554-1564.
  • Hetrick, E. M.; Shin, J. H.; Paul, H. S.; Schoenfisch, M. H. Anti-biofilm efficacy of nitric oxide-releasing silica nanoparticles, Biomaterials, 2009, 30, 2782-2789.
  • Riccio, D. A.; Dobmeier, K. P.; Hetrick, E. M.; Privett, B. J.; Paul, H. S.; Schoenfisch, M. H. Nitric oxide-releasing S-nitrosothio-modified xerogels, Biomaterials, 2009, 30, 4494-4502.
  • Paul, H. S.; Schoenfisch, M. H. Nitric Oxide-Releasing Subcutaneous Glucose Sensors. In In Vivo Glucose Sensing; Cunningham, D. D., Stenken J. S., Eds.; Chemical Analysis, Vol 174; Wiley & Sons: Hoboken, NJ, 2010; pp 243-267.
  • Bernotas, R. C.; Kaufman, D. H.; Singhaus, R. R.; Ullrich, J. W.; Unwalla, R.; Quinet, E.; Nambi, P.; Wilhelmsson, A.; Goos-Nilsson, A.; Wrobel, J. 4-(3-Aryloxyaryl)quinoline alcohols are liver X receptor agonists, Bioorganic & Medicinal Chemistry, 2009, 17(23), 8086-8092.
  • Bernotas, R. C.; Singhaus, R.; Kaufman, D.; Ullrich, J. W.; Fletcher, H.; Quinet, E.; Nambi, P.; Unwalla, R.; Wilhelmsson, A.; Goos-Nilsson, A.; Farnegardh, M.; Wrobel, J. Biarylether amide quinolines as liver X receptor agonists, Bioorganic & Medicinal Chemistry, 2009, 17(4), 1663-1670.
  • Crawley, M. L.; Phipps, K. M.; Goljer, I.; Mehlmann, J.; Lundquist, J.; Ullrich, J. W.; Yang, C.; Mahaney, P. E. Efficient, Regioselective Palladium-Catalyzed Tandem Heck-Isomerization Reaction of Aryl Bromides and Non-Allylic Benzyl Alcohols Organic Letters, 2009, 11(5), 1183-1185.
  • Wrobel, J. E.; Hu, B.; Collini, M.; Jetter, J. W.; Bernotas, R. C.; Kaufman, D. H.; Singhaus, R. Jr.;  Ullrich, J. W.; Morris, R. L.; Unwalla, R. J. Preparation of quinoline as modulators of Liver X receptors (LXRs), U.S. Pat. Appl. Publ., 2009, US 2009069373.
  • Bernotas, R. C.; Ullrich, J. W.; Travins, J. M.; Wrobel, J. E.; Unwalla, R. J. Preparation of quinazoline compounds as modulators of Liver X receptors (LXRs), PCT Int. Appl., 2009.
  • Steves, J. E.; Kennedy, M. D.; Chiang, K. P.; Kassel, W. S.; Dougherty, W. G.; Dudley, T. J.; Zubris, D. L. Synthesis of a bulky bis(imino)pyridine compound:  A methodology for systematic variation of steric bulk and energetic implications for metalation, Dalton Trans., 2009, 1214-1222.

Presentations

  • Burke, L. A.; Fazen, P. J., “Cascading 1,3-Dipolar Cycloadditions:  Combined and Consecutive Mechanisms to Azirines up to Pentazenes and Pentazoles," Sanibel Symposium 49, Quantum Theory Project, University of Florida, 2009.
  • Xu, Z. H.; Wang, Q. M.; Zhuang, Y. L.; Davis, H. M.; Zhou, H., "Bioavailability of Golimumab, an Anti-Tumor Necrosis Factor-Human Monoclonal Antibody," Administered Subcutaneously at Three Different Injection Sites in Healthy Subjects, ASCPT, March 2009.
  • Rowland, G. A.; Torres, A. S.; Grannas, A. M., "Partitioning and Transport of Organochlorine Pollutants in the Arctic: From Snowfall to Snowmelt" National Meeting of the American Geophysical Union, San Francisco, CA, December 14-18, 2009.
  • Palechar, J. B., "Gene Transcription in Trypansomes," Invited Presentation, University of the Sciences in Philadelphia, October 28, 2009.
  • Ullrich, J. W.; Morris, R. L.; Bernotas, R. C.; Travins, J. M.; Jetter, J.; Unwalla, R.; Nambi, P.; Quinet, E.; Wilhelmsson, A.; Goos-Nilsson, A.; Enroth, C.; Wrobel, J., "Synthesis and LXR activity of biaryl sulfones," 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009.
  • Singhaus, R. R.; Bernotas, R. C.; Ullrich, J. W.; Kaufman, D. H.; Morris, R. L.; Nambi, P.; Quinet, E.; Unwalla, R. J.; Wilhelmsson, A.; Goos-Nilsson, A.; Enroth, C.; Wrobel, J., "Design and synthesis of biarylether sulfonamide quinolines as LXR agonists," 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009.
  • Jetter, J. W.; Bernotas, R. C.; Hu, B.; Ullrich, J. W.; Travins, J. M.; Kaufman, D. H.; Unwalla, R. J.; Wrobel, J.; Goos-Nilsson, A.; Wilhelmsson, A.; Morris, R.; Quinet, E.; Nambi, P.,"Synthesis and structure activity relationship of quinoline based amine derivatives as liver X receptors (LXRs) modulators," 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009.
  • Bernotas, R. C.; Singhaus, R. R.; Kaufman, D. H.; Ullrich, J. W.; Morris, R. L.; Unwalla, R. J.; Nambi, P.; Quinet, E.; Wilhelmsson, A.; Goos-Nilsson, A. Enroth, C.; Wrobel, J.,"Biarylether quinoline sulfones are high affinity, potent liver X receptor agonists," 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009.
  • Zubris, D. L., "Synthesis of sterically hindered bis(imino)pyridine ligands and structural implications for metalation," Invited Presentation, St. Joseph’s University, Philadelphia, PA, October 14, 2009.
  • Axtell, J. C.; Thai, S. D.; Morton, L. A.; Kassel, W. S.; Dougherty, W. .; Zubris, D. L., "Synthesis and meso to rac isomerization of rac/meso-ansa-zirconocenes with a phosphine linker," National Meeting of the American Chemical Society, Salt Lake City, UT, March 22-26, 2009.
  • Steves, J. E.; Kennedy, M. D.; Chiang, K. P.; Kassel, W. S.; Dougherty, W. G.; Dudley, T. J.; Zubris, D. L., "Synthesis of a sterically hindered bis(imino)pyridine compound as a potential ligand for iron(II)," National Meeting of the American Chemical Society, Salt Lake City, UT, March 22-26, 2009.
  • Kennedy, M. D.; Steves, J. E.; Chiang, K. P.; Kassel, W. S.; Dougherty, W. G.; Dudley, T. J.; Zubris, D. L., "New methodology for synthesis of Cs- and C1-symmetric bis(imino)pyridines and energetic implications for metalation," National Meeting of the American Chemical Society, Salt Lake City, UT, March 22-26, 2009.